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The valence of the microorganisms could be determined by pressing calmly on the cowl slip with a pointed object just like the tip of a pen. When pink blood cells grow to be infested with the higher valence progress forms of the primary parasite, their urge to merge pulls the RBCs together. Copulation between excessive valence microorganisms on adjoining RBC membranes account for blood sugar regulation formula the rouleau formations. The presence of large rouleau may be detrimental to patients suffering from occlusive vascular diseases because it causes impairment of blood flow in the small vessels that can compromise the pink blood cells’ capability to trade carbon dioxide and oxygen gases. This can cause greater blood stress so as to increase the availability of blood and oxygen to the tissue. Peripheral blood sugar regulation formula smears display rouleau when factors that improve ESR (erythrocyte sedimentation charge) are present. Anemia, by rising the ratio of RBCs to plasma, increases rouleau formation and accelerates sedimentation.
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